Preclinical ocular research requires non-invasive, repeatable imaging that can detect meaningful changes in the living eye. Two imaging tools, color fundus photography (FP) and optical coherence tomography (OCT), have become central to that effort, providing complementary views of retinal structure that together cover what neither...
Delivering a drug to the retina is a technically demanding problem. The eye is a small, enclosed space with multiple tissue layers, each with its own properties and barriers. Getting a drug or therapy to the right layer, in sufficient quantity, without damaging the tissue...
The electroretinogram (ERG) has been a standard tool in clinical ophthalmology for decades, but its role in preclinical research has quietly expanded into territory well beyond its origins in retinal disease diagnosis....
Visual evoked potentials (VEPs) are the electrical signals the brain generates in response to light, and they have long been a fixture of clinical neurology. But in preclinical research, they are earning a second reputation: as sensitive, quantitative measures capable of tracking disease progression and...