Therapeutic Expertise: Ophthalmology

Our team are experts in managing and evaluating images, especially with ocular diseases affecting the retina. As a trusted partner to sponsors and CROs, we provide domain expertise, innovative imaging tools, and scalable solutions.

Ophthalmology Imaging Services

MERIT’s comprehensive portfolio of ophthalmic services ensures your research is conducted accurately and efficiently.
  • Site Image Acquisition & Upload
  • Image Read & Adjudication
  • Endpoint Assessments
  • Protocol Design & Consultation
  • Site Certification & Training
  • Site Support
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SPECIALIZING IN:

  • Diabetic Retinopathy
  • Inherited Retinal Diseases (IRDs)
  • Dry AMD
  • Endothelial Cell Health
  • Retinal Vein Occlusion (RVO)
  • Dry Eye Disease
  • Anterior Segment
  • Wet AMD
  • Safety Endpoint
  • Device/AI
  • Uveitis
  • Retinopathy of Prematurity (ROP)
  • Glaucoma
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KEY OPHTHALMOLOGY ENDPOINT OFFERINGS:

Morphology
  • OCT/OCTA
  • FAF
  • Color FP
  • FA/ICGA
  • Slit Lamp Imaging
  • Specular Microscopy
  • B Scan Ultrasonography
  • IOL Rotational Analysis
Function
  • BCVA/LLVA
  • Microperimetry
  • Electroretinogram
  • Visual Evoked Potential
  • Pupillometry
  • MLMT
  • Light/Dark Adaptation
  • Static & Kinetic Perimetry
  • Contrast Sensitivity
  • Ocular Motor Instability

OPHTHALMOLOGY EXPERTISE

A successful multi-center trial requires intrinsic understanding of various imaging techniques, developing meaningful outcome correlations, and formulating computational methodologies. Our insightful experts (several are board-certified ophthalmologists) help guide your selection of the right biomarkers that accurately reflect the characteristics of disease progression and treatment effects.

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Ophthalmology Studies by Indication

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With MERIT, you benefit from the following:

  • High-quality, reliable data review and interpretation:
    • MERIT’s team of knowledgeable ophthalmologists (several are board-certified) provide domain expertise to assure high-quality, consistent data review and interpretation
  • Innovative Comprehensive Data Platform:
    • Our cloud-based EXCELSIOR™ platform allows immediate transfer of data directly from qualified sites to a central database for review without installing software or configuring firewalls
  • Competitive Pricing and Shortened Timelines:
    • Sponsors benefit by gaining efficiencies due to our refined and standardized processes.

With MERIT, your ophthalmology study data and images can easily be shared between clinical sites, reading centers, CROs, and sponsors for maximum transparency. This makes managing global ophthalmic trials involving multiple reading centers and analysis of multiple modalities not only feasible, but practical.

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YOUR OPHTHALMOLOGY TRIALS

With Excelsior

MERIT’s Cloud-based Software Platform

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EXCELSIOR imaging platform logo — MERIT's cloud-based oncology imaging trial software

Software User Testimonial

The EXCELSIOR™ portal has become one of my favorite platforms for image submission. As an ophthalmic photographer managing high volumes of research imaging, I appreciate its intuitive, well-organized design, which makes uploading and verifying submissions quick and straightforward. The support team has also been consistently responsive and helpful. Overall, it’s been a pleasure to work with, bringing real efficiency and reliability to our research imaging operations.

– OPHTHALMIC PHOTOGRAPHER, OPERATIONS COORDINATOR

Reading Center Services

MERIT provides consistent, high-quality independent reading center services.

Benefits:

  • Reduced image acquisition variability among imaging sites
  • Minimized bias in endpoint evaluation
  • Increased data integrity in collection and interpretation
  • Collaborative, partnership-driven approach
  • Standardized & accurate processes
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OPHTHALMIC CASE STUDIES

BCVA Services

  • Full, Abbreviated, and Express Certifications for VA Examiners
  • Full and Express Certifications for VA Rooms
  • Certificates Maintained in EXCELSIOR
  • Confirmation of Acceptable BCVA Equipment
  • Scheduling, Tracking & Reporting of BCVA Certification Study Activities
  • Visual Acuity Certifications: ETDRS, Low Luminance, Contrast Sensitivity & Reading Assessments
  • VA Room Equipment Procurement
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Endothelial Cell Count (ECC) Analysis

MERIT provides ECC analysis for the following ocular clinical trials:

  • Corneal dystrophies, corneal edemas, keratoconus, etc.
  • Cataract surgery
  • Intraocular Lens (IOL) implants
  • Safety assessment for intravitreal injection (nAMD, DME)
  • Safety assessment for ocular implants (Glaucoma)
  • Safety assessment for eyedrops (dry eye disease, etc.)
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Let's Make Your
Project a Reality

Connect with us to learn more about how our expertise and approach can support bringing your product to market on-time and on-budget. Your success is our priority.