Therapeutic Expertise: Ophthalmology

OPHTHALMOLOGY IMAGING SOLUTIONS

MERIT is an ophthalmology reading center supporting Phase I – IV clinical trials. Our team are experts in managing and evaluating images, especially with ocular diseases affecting the retina. As a trusted partner to sponsors and CROs, we provide domain expertise, innovative imaging tools, and scalable solutions.

With MERIT, you benefit
from the following:

  • High-quality, reliable data review and interpretation: MERIT’s team of knowledgeable ophthalmologists (several are board-certified) provide domain expertise to assure high-quality, consistent data review and interpretation
  • Innovative Comprehensive Data Platform: Our cloud-based EXCELSIOR™ platform allows immediate transfer of data directly from qualified sites to a central database for review without installing software or configuring firewalls
  • Competitive Pricing and Shortened Timelines: Sponsors benefit by gaining efficiencies due to our refined and standardized processes.

With MERIT, your ophthalmology study data and images can easily be shared between clinical sites, reading centers, CROs, and sponsors for maximum transparency. This makes managing global ophthalmic trials involving multiple reading centers and analysis of multiple modalities not only feasible, but practical.

OUR OPHTHALMIC PROCESS

Messages are sent directly to the project team from our data acquisition platform, allowing for smoother tracking of images

Our data acquisition platform makes site queries more efficient.

Immediate quality control enables quick confirmation that images have been acquired correctly

Prompt feedback to the site prevents further images from being acquired incorrectly

OPHTHALMOLOGY IMAGING SERVICES

MERIT’s comprehensive portfolio of ophthalmic services ensures your research is conducted accurately and efficiently. We seamlessly manage the imaging components of your trial, creating efficiencies for your drug development.

OUR IMAGING SERVICES:

  • Protocol Design & Consultation
  • Site Certification
  • Image Acquisition & Upload
  • Image Read & Adjudication
  • Imaging Site Support
  • Study Management
  • Quality Assurance

IMAGING MODALITIES:

Color FP
Microperimentry
Light/Dark Adaption
Slit Lamp Imaging
OCT
Static & Kinetic Perimetry
Electroretinogram
Specular Microscopy
FAF
Pupillometry
Visual Evoked Potential
B Scan Ultrasonography
FA/ICGA
Full Field Stimuli Test
Ocular Motor Instability
IOL Rotational Analysis

BCVA Services

Full, Abbreviated, and Express Certifications for VA Examiners

Full and Express Certifications for VA Rooms

Certificates Maintained in EXCELSIORTM

Confirmation of Acceptable BCVA Equipment

Scheduling, Tracking & Reporting of BCVA Certification Study Activities

Visual Acuity Certifications: ETDRS, Low Luminance, Contrast Sensitivity & Reading Assessments

VA Room Equipment Procurement

Endothelial Cell Count (ECC) Analysis

MERIT provides ECC analysis for the following ocular clinical trials:

  • Corneal dystrophies, corneal edemas, keratoconus, etc.
  • Cataract surgery
  • Intraocular Lens (IOL) implants
  • Safety assessment for intravitreal injection (nAMD, DME)
  • Safety assessment for ocular implants (Glaucoma)
  • Safety assessment for eyedrops (dry eye disease, etc.)

OPHTHALMOLOGY EXPERTISE

Adept analysis and proven expertise with MERIT.

A successful multi-center trial requires intrinsic understanding of various imaging techniques, developing meaningful outcome correlations, and formulating computational methodologies. Our insightful experts (several are board-certified ophthalmologists) help guide your selection of the right biomarkers that accurately reflect the characteristics of disease progression and treatment effects.

EXPERIENCE BY THE NUMBERS

OPHTHALMOLOGY STUDIES BY INDICATION

OPHTHALMIC CASE STUDIES

IMAGING SOFTWARE

MERIT’s cloud-based EXCELSIOR™ platform allows immediate transfer of data directly from qualified sites to a central database for review without installing software or configuring firewalls. Our exceptional reading center services for ophthalmic imaging can be easily configured to meet sponsor and study requirements. EXCELSIOR, built specifically for supporting image data collection and management for ophthalmic clinical trials, offers the latest web and imaging technologies for data standardization, analysis, grading, and reporting.

OPHTHALMOLOGY DISEASE STATES

AMD

Age Related Macular Degeneration (AMD) is a common eye condition and leading cause of vision loss among people aged 50 and over.

UVEITIS

Uveitis refers to the inflammation of structures on the uveal tract and causes 10-15% of cases of legal blindness in the US.

DR/DME

Diabetic Retinopathy/Diabetic Macular Edema (DR/DME) is the most common cause of vision loss among people with diabetes and a leading cause of vision impairment/blindness among working-age adults. Chronically high blood sugar is associated with damage to the blood vessels in the retina.

RVO

Retinal Vein Occlusion (RVO) is a common vascular disorder of the retina and one of the most common causes of vision loss worldwide.

INHERITED RETINAL DISEASES

Therapeutic options are under investigation for the treatment of previously untreatable Rare or Orphan diseases in ophthalmology such as Retinitis Pigmentosa, Usher Syndrome, Stargardt Disease and Leber Congenital Amaurosis.

preview of solution guide pdf
MERIT Ophthalmology Imaging Solutions Guide
preview of solution guide pdf
MERIT Reading Center Services Solutions Guide

TELL US ABOUT
YOUR PROJECT

Connect with us to learn more about how our expertise and approach can support bringing your product to market on-time and on-budget. Your success is our priority.